What does Spravato feel like? Here's the inside scoop.

If you're looking into new treatments for depression, you're likely wondering what does Spravato feel like before you actually sit down in that doctor's chair. It's a totally valid question because, unlike a standard antidepressant that you just swallow with a glass of water and forget about, Spravato (esketamine) is an experience. It's a session. It's a two-hour block of time where your brain goes on a bit of a journey, and knowing what to expect can take a lot of the anxiety out of the process. ...

May 12, 2026 · 6 min · Robyn Caleb